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Tyler Perry’s House of Payne is an American comedy-drama television series created and produced by playwright, director, and producer Tyler Perry. The show revolved around a multi-generational family living under one roof in Atlanta led by patriarch Curtis Payne and his wife Ella. The show premiered in syndication on June 21, 2006, and new episodes were broadcast exclusively on TBS from June 6, 2007, until August 10, 2012. While primarily a comedy sitcom, House of Payne was known for featuring dark themes and subject matter, such as substance abuse and addiction. It also had elements of slapstick. The storyline of the show is serialized, with many references to past episodes, creating a continuing story arc.

House of Payne aired more episodes than any other television series with a predominantly African American cast, surpassing The Jeffersons, Family Matters and The Cosby Show.